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Apraclonidine causes severe lethargy in infants New research suggests that an eyedrop utilized to diagnose a rare syndrome in infants could cause severe lethargy enduring up to 10 hours and requiring medical center admission and oxygen administration. Patrick Watts and coauthors defined five cases of severe drowsiness or unresponsiveness after infants under six months of age were administered 1 percent apraclonidine eyedrops. Related StoriesBoston Kids's and Rock Health synergy to accelerate advancement of pediatric health technologiesCHOP's Buerger Middle for Advanced Pediatric Care celebrates grand openingStudy: Post medical center syndrome is significant risk factor for individuals undergoing elective surgeryApraclonidine originated to lower intraocular pressure and minimize the systemic side effects associated with the use of its parent drug, clonidine super-avana.com .

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The highest focus of NexACT enhancer tested did not affect the viability of the buccal cells, suggesting a secure range for clinical make use of. Dr. Bassam Damaj, President and Chief Executive Officer of Apricus Bio, noted, ‘The buccal path of delivery represents an additional, new program of NexACT and possibly enables us to deliver drugs that can’t be shipped via the oral, intravenous or transdermal path.’ The abstract is available at:.. Apricus announces publication of NexACT technology data in Pharmaceutics Journal Apricus Biosciences, Inc. The article, entitled, ‘Enhanced in vitro Transbuccal Drug Delivery of Ondansetron HCl,’ highlights NexACT enhancers’ ability to significantly improve permeation of ondansetron, a drug used to treat nausea and vomiting associated with chemotherapy and post medical procedures, through porcine buccal tissue.HCl, one of the NexACT technology’s proprietary enhancers, provided the very best improvements in comparison with additional enhancers and other technologies .