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In view of potential for clinical applications, there are some common key challenges and questions. The question of concentrates on critical questions how, Though several use of stem cells public , the risk of cancer in the recipient and whether the destination stem cell therapy is to as organ as an organ-specific cells to enhance provide. – letter you in a comment of the progress and challenge with the implementation stem cell therapies for clinical disease, Michael A. Matthay, Cardiovascular Research Institute, University of California in San Francisco, observes that the progress made by reach in the in in the use allogeneic and autologous hematopoietic stem for the effective treatment of hematologic malignancies should serve as a model, as is clinical application yet embryonic stem cell, induced pluripotent stem cells, endothelial progenitor cells, and mesenchymal stem can be achieved. Although several challenges will active in translation stem cell treatment Last treatment both acute and chronic human diseases, potential for developing effective of new cell – based therapy has high.