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Two-thirds of adults aged 65 years and old with dementia possess Alzheimer’s disease , and the number of AD cases is predicted to increase with the growing older adult population. Although genetic risk factors for AD have already been identified, only a fraction of Advertisement cases can be explained by particular gene mutations. Studies of twins have been useful in investigating the relative need for genetic and environmental influences in disease development. For example, if similar twins usually do not both have a disease, environmental factors may be implicated because of its occurrence.D., University of Southern California, Los Angeles, and colleagues evaluated 11,884 pairs of twins from the Swedish Twin Registry to examine the association between genetic and environmental influences and AD.