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Growth and progression to metastasis.

Fisher, M.Ph., Ph.D., professor and seat of the Section of Human being and Molecular Genetics, director of the VCU Institute of Molecular Medicine in the VCU School of Medicine, and plan leader of Cancers Molecular Genetics at the Massey Cancer tumor Center, the team has shown that astrocyte elevated gene-1, AEG-1, a malignancy promoting gene, is involved in both oncogenic transformation, which may be the conversion of a standard cell to a tumor cell, and angiogenesis, which may be the formation of fresh blood cells. Oncogenic transformation and angiogenesis are crucial for tumor development, growth and progression to metastasis.