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None of the preparations reached all the requirements for safety.

Does add Simehicone To Sodium Phosphate Bowel Preparation Benefit colonoscopybowel preparation has been reported inadequate in 10 percent-75 percent of the colonoscopies. None of the preparations reached all the requirements for safety, acceptance by patients with negligible discomfort and quick cleaning. Polyethylene glycol is the gold standard gold standard for colonoscopy bowel preparation and aqueous sodium phosphate was an alternative treatment with PEG solution . This consensus also stated that adjunctive therapy, such as bisacodyl, metoclopramide, and simethicone, was shown to improve the quality of bowel preparation. Simethicone acts as an addition to intestinal preparationwith the purpose of reducing the formation of foam and to improve visualization during colonoscopy.

Research from Thailand led by Abhasnee Sobhonslidsuk addressed this issue. A prospective, double – blind, randomized, placebo-controlled study was conducted with 124 patients participated. All patients were assigned to receive 2 doses of sodium phosphate plus 240 mg simethicone tablet or placebo bowel preparations. Visibility was blindly assessed for the amount of air bubbles and adequacy of bowel preparation. Total colonoscopic duration, side effects of medications, the satisfaction of endoscopists and patients were also compared.