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In particular.

In particular, they found that gait disturbances and death of nerve cells in several regions of the brain, a result of the GSK-3 – protein inhibition an increased nuclear localization NFATc3 / 4 proteins and increased led to the death-inducing molecule, were Fas ligand. The authors hope that these data could new ideas for combination therapies, the toxicity of lithium which has been proposed as a treatment for Alzheimer’s disease to provide reduce.

However, Raquel G mez Sintes and Jos? have at the CSIC / UAM, Spain, now a molecular pathway by chronic administration of therapeutic doses of lithium has accrued negative effects in mice.