You are currently browsing the archives for 15 March 2015.
Displaying 1 entry.

That is what occurred in this study.

Rats tend to sites where they received morphine return and locations where they got to avoid a KOR agonist. That is what occurred in this study, except that the single cocaine exposure significantly increased both their attraction to the places where they. Received morphine and their aversion to the places where they had the KOR agonists received.

Before the rats were introduced to the training environment, they were injected with a dose of cocaine. They were then placed in a chamber or the other. One group with with morphine over a two-to four-day period, while another group was given a similar drug called a kappa – opioid receptor agonist that produces an unpleasant or aversive effect.